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Electrophysiological measurement of ion channels on plasma/organelle membranes using an on-chip lipid bilayer system

Ion channels are located in plasma membranes as well as on mitochondrial, lysosomal, and endoplasmic reticulum membranes. They play a critical role in physiology and drug targeting. It is particularly challenging to measure the current mediated by ion channels in the lysosomal and the endoplasmic re...

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Detalles Bibliográficos
Autores principales: Kamiya, Koki, Osaki, Toshihisa, Nakao, Kenji, Kawano, Ryuji, Fujii, Satoshi, Misawa, Nobuo, Hayakawa, Masatoshi, Takeuchi, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269590/
https://www.ncbi.nlm.nih.gov/pubmed/30504856
http://dx.doi.org/10.1038/s41598-018-35316-4