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Electrophysiological measurement of ion channels on plasma/organelle membranes using an on-chip lipid bilayer system
Ion channels are located in plasma membranes as well as on mitochondrial, lysosomal, and endoplasmic reticulum membranes. They play a critical role in physiology and drug targeting. It is particularly challenging to measure the current mediated by ion channels in the lysosomal and the endoplasmic re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269590/ https://www.ncbi.nlm.nih.gov/pubmed/30504856 http://dx.doi.org/10.1038/s41598-018-35316-4 |