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Mechanical stress contributes to osteoarthritis development through the activation of transforming growth factor beta 1 (TGF-β1)

OBJECTIVES: The role of mechanical stress and transforming growth factor beta 1 (TGF-β1) is important in the initiation and progression of osteoarthritis (OA). However, the underlying molecular mechanisms are not clearly known. METHODS: In this study, TGF-β1 from osteoclasts and knee joints were ana...

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Detalles Bibliográficos
Autores principales: Zhang, R-K., Li, G-W., Zeng, C., Lin, C-X., Huang, L-S., Huang, G-X., Zhao, C., Feng, S-Y., Fang, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269596/
https://www.ncbi.nlm.nih.gov/pubmed/30581556
http://dx.doi.org/10.1302/2046-3758.711.BJR-2018-0057.R1