Bromodomain protein inhibition: a novel therapeutic strategy in rheumatic diseases

The reading of acetylation marks on histones by bromodomain (BRD) proteins is a key event in transcriptional activation. Small molecule inhibitors targeting bromodomain and extra-terminal (BET) proteins compete for binding to acetylated histones. They have strong anti-inflammatory properties and exh...

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Detalles Bibliográficos
Autor principal: Klein, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Animal Models
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269638/
https://www.ncbi.nlm.nih.gov/pubmed/30564450
http://dx.doi.org/10.1136/rmdopen-2018-000744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269638/
https://www.ncbi.nlm.nih.gov/pubmed/30564450
http://dx.doi.org/10.1136/rmdopen-2018-000744

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