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Semi-Synthesis of Labeled Proteins for Spectroscopic Applications

Since the introduction of SPPS by Merrifield in the 60s, peptide chemists have considered the possibility of preparing large proteins. The introduction of native chemical ligation in the 90s and then of expressed protein ligation have opened the way to the preparation of synthetic proteins without s...

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Detalles Bibliográficos
Autores principales: De Rosa, Lucia, Russomanno, Anna, Romanelli, Alessandra, D’Andrea, Luca Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269674/
https://www.ncbi.nlm.nih.gov/pubmed/23282535
http://dx.doi.org/10.3390/molecules18010440