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Structural Requirements for the Antifungal Activities of Natural Drimane Sesquiterpenes and Analogues, Supported by Conformational and Electronic Studies

Seventeen drimanes including polygodial (1), isopolygodial (2), drimenol (3) and confertifolin (4) obtained from natural sources and the semi-synthetic derivatives 5–17 obtained from 1–3, were evaluated in vitro for antifungal properties against a unique panel of fungi with standardized procedures b...

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Detalles Bibliográficos
Autores principales: Derita, Marcos, Montenegro, Iván, Garibotto, Francisco, Enriz, Ricardo D., Fritis, Mauricio Cuellar, Zacchino, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269676/
https://www.ncbi.nlm.nih.gov/pubmed/23385340
http://dx.doi.org/10.3390/molecules18022029