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Hexachlorocyclotriphosphazene (HCCP)-Mediated Direct Formation of Thioethers and Ethers from Quinazolin-4(3H)-ones

A hexachlorocyclotriphosphazene (HCCP)-mediated direct formation of quinazoline (thio)ethers from quinazolin-4(3H)-ones has been developed. Treatment of quinazolin-4(3H)-ones with HCCP, diisopropylethylamine (DIPEA), and thiophenols resulted in formation of the corresponding 4-arylthioquinazoline de...

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Detalles Bibliográficos
Autores principales: Hu, Baoxiang, Zhang, Xiaochu, Sheng, Lili, Guo, Ming, Shen, Zhenlu, Hu, Xinquan, Sun, Nan, Mo, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269698/
https://www.ncbi.nlm.nih.gov/pubmed/23676469
http://dx.doi.org/10.3390/molecules18055580