Xanthene and Xanthone Derivatives as G-Quadruplex Stabilizing Ligands

Following previous studies on anthraquinone and acridine-based G-quadruplex ligands, here we present a study of similar aromatic cores, with the specific aim of increasing G-quadruplex binding and selectivity with respect to duplex DNA. Synthesized compounds include two and three-side chain xanthone...

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Detalles Bibliográficos
Autores principales: Altieri, Alessandro, Alvino, Antonello, Ohnmacht, Stephan, Ortaggi, Giancarlo, Neidle, Stephen, Nocioni, Daniele, Franceschin, Marco, Bianco, Armandodoriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269716/
https://www.ncbi.nlm.nih.gov/pubmed/24177701
http://dx.doi.org/10.3390/molecules181113446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269716/
https://www.ncbi.nlm.nih.gov/pubmed/24177701
http://dx.doi.org/10.3390/molecules181113446

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