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Xanthene and Xanthone Derivatives as G-Quadruplex Stabilizing Ligands
Following previous studies on anthraquinone and acridine-based G-quadruplex ligands, here we present a study of similar aromatic cores, with the specific aim of increasing G-quadruplex binding and selectivity with respect to duplex DNA. Synthesized compounds include two and three-side chain xanthone...
Autores principales: | Altieri, Alessandro, Alvino, Antonello, Ohnmacht, Stephan, Ortaggi, Giancarlo, Neidle, Stephen, Nocioni, Daniele, Franceschin, Marco, Bianco, Armandodoriano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269716/ https://www.ncbi.nlm.nih.gov/pubmed/24177701 http://dx.doi.org/10.3390/molecules181113446 |
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