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Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation

Triptolide (TP) often causes adverse reactions in the gastrointestinal tract when it is administered orally. This study aimed to prepare and optimize triptolide-loaded solid lipid nanoparticles (TP-SLN) with reduced gastric irritation. The microemulsion technique was used to formulate TP-SLN employi...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Gu, Conghui, Peng, Fan, Liu, Wei, Wan, Jiangling, Xu, Huibi, Lam, Christopher Waikei, Yang, Xiangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269717/
https://www.ncbi.nlm.nih.gov/pubmed/24172242
http://dx.doi.org/10.3390/molecules181113340