Cargando…

Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation

Triptolide (TP) often causes adverse reactions in the gastrointestinal tract when it is administered orally. This study aimed to prepare and optimize triptolide-loaded solid lipid nanoparticles (TP-SLN) with reduced gastric irritation. The microemulsion technique was used to formulate TP-SLN employi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Cong, Gu, Conghui, Peng, Fan, Liu, Wei, Wan, Jiangling, Xu, Huibi, Lam, Christopher Waikei, Yang, Xiangliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269717/ https://www.ncbi.nlm.nih.gov/pubmed/24172242 http://dx.doi.org/10.3390/molecules181113340

Ejemplares similares

Nanostructured lipid carriers as a novel oral delivery system for triptolide: induced changes in pharmacokinetics profile associated with reduced toxicity in male rats
por: Zhang, Cong, et al.
Publicado: (2014)

Biological Activity and Safety of Tripterygium Extract Prepared by Sodium Carbonate Extraction
por: Fang, Wei, et al.
Publicado: (2012)

Lipid nanoparticles loading triptolide for transdermal delivery: mechanisms of penetration enhancement and transport properties
por: Gu, Yongwei, et al.
Publicado: (2018)

A New Strategy for Enhancing the Oral Bioavailability of Drugs with Poor Water-Solubility and Low Liposolubility Based on Phospholipid Complex and Supersaturated SEDDS
por: Zhou, Hui, et al.
Publicado: (2013)

Mechanochemical preparation of triptolide-loaded self-micelle solid dispersion with enhanced oral bioavailability and improved anti-tumor activity
por: Zhu, Dabu, et al.
Publicado: (2022)

Ultrasound Guided Intra-Articular Injection of Triptolide-loaded Solid Lipid Nanoparticle for Treatment of Antigen-Induced Arthritis in Rabbits
por: Li, Shilin, et al.
Publicado: (2022)

Triptolide attenuates irritable bowel syndrome via inhibiting ODC1
por: Zhu, Ning, et al.
Publicado: (2023)

Naringenin-loaded solid lipid nanoparticles: preparation, controlled delivery, cellular uptake, and pulmonary pharmacokinetics
por: Ji, Peng, et al.
Publicado: (2016)

Preparation, Characterization and Pharmacokinetics of Tolfenamic Acid-Loaded Solid Lipid Nanoparticles
por: Xu, Wei, et al.
Publicado: (2022)

Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles
por: Omwoyo, Wesley Nyaigoti, et al.
Publicado: (2014)

Preparation and Evaluation of Montelukast Sodium Loaded Solid Lipid Nanoparticles
por: Priyanka, K, et al.
Publicado: (2012)

Preparation, in vitro and in vivo Evaluation of Thermosensitive in situ Gel Loaded with Ibuprofen-Solid Lipid Nanoparticles for Rectal Delivery
por: Huang, Chun-hui, et al.
Publicado: (2022)

Buparvaquone loaded solid lipid nanoparticles for targeted delivery in theleriosis
por: Soni, Maheshkumar P., et al.
Publicado: (2014)

Superior in vitro anticancer effect of biomimetic paclitaxel and triptolide co-delivery system in gastric cancer
por: Wang, Siwan, et al.
Publicado: (2021)

Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil
por: Shi, Feng, et al.
Publicado: (2012)

Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles
por: Xie, Shuyu, et al.
Publicado: (2011)

Preparation, in vitro and in vivo Evaluation of Thermosensitive in situ Gel Loaded with Ibuprofen-Solid Lipid Nanoparticles for Rectal Delivery [Retraction]
Publicado: (2022)

Improved Dermal Delivery of Cyclosporine A Loaded in Solid Lipid Nanoparticles
por: Essaghraoui, Abderrazzaq, et al.
Publicado: (2019)

Preparation, optimization, and characterization of chitosan-coated solid lipid nanoparticles for ocular drug delivery
por: Wang, Feng-zhen, et al.
Publicado: (2018)

Pulmonary delivery of triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX antibody for lung cancer therapy
por: Lin, Congcong, et al.
Publicado: (2017)

Transdermal delivery of triptolide–phospholipid complex to treat rheumatoid arthritis
por: Liu, Xin-Yi, et al.
Publicado: (2021)

Delivery of triptolide: a combination of traditional Chinese medicine and nanomedicine
por: Sun, Rui, et al.
Publicado: (2022)

Enhanced Transdermal Delivery of Concentrated Capsaicin from Chili Extract-Loaded Lipid Nanoparticles with Reduced Skin Irritation
por: Anantaworasakul, Phunsuk, et al.
Publicado: (2020)

Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method
por: Duong, Van-An, et al.
Publicado: (2020)

Development of Triptolide Self-Microemulsifying Drug Delivery System and Its Anti-tumor Effect on Gastric Cancer Xenografts
por: Xie, Minghua, et al.
Publicado: (2019)

Ocular Delivery of Bimatoprost-Loaded Solid Lipid Nanoparticles for Effective Management of Glaucoma
por: Satyanarayana, Sandeep Divate, et al.
Publicado: (2023)

Preparation and Characterization of Catalase-Loaded Solid Lipid Nanoparticles Protecting Enzyme against Proteolysis
por: Qi, Ce, et al.
Publicado: (2011)

Preparation and evaluation of tacrolimus-loaded thermosensitive solid lipid nanoparticles for improved dermal distribution
por: Kang, Ji-Hyun, et al.
Publicado: (2019)

Sorafenib and triptolide loaded cancer cell-platelet hybrid membrane-camouflaged liquid crystalline lipid nanoparticles for the treatment of hepatocellular carcinoma
por: Li, Zhe, et al.
Publicado: (2021)

Enhanced Nasal Mucosal Delivery and Immunogenicity of Anti-Caries DNA Vaccine through Incorporation of Anionic Liposomes in Chitosan/DNA Complexes
por: Chen, Liulin, et al.
Publicado: (2013)

Cubic and hexagonal liquid crystals as drug carriers for the transdermal delivery of triptolide
por: Shan, Qian-Qian, et al.
Publicado: (2019)

Glutathione-Loaded Solid Lipid Microparticles as Innovative Delivery System for Oral Antioxidant Therapy
por: Bertoni, Serena, et al.
Publicado: (2019)

Application of Response Surface Method for Preparation, Optimization, and Characterization of Nicotinamide Loaded Solid Lipid Nanoparticles
por: Vakilinezhad, Molood Alsadat, et al.
Publicado: (2018)

Highly efficient retinal gene delivery with helper-dependent adenoviral vectors
por: Lam, Simon, et al.
Publicado: (2014)

Renal-targeted delivery of triptolide by entrapment in pegylated TRX-20-modified liposomes
por: Yuan, Zhi-xiang, et al.
Publicado: (2017)

Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics
por: Fang, Yi-Ping, et al.
Publicado: (2016)

Sustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation
por: Lu, Mengmeng, et al.
Publicado: (2017)

Preparation and Characterization of Magnetic Solid Lipid Nanoparticles as a Targeted Drug Delivery System for Doxorubicin
por: Soltani, Abbas, et al.
Publicado: (2023)

Preparation, Statistical Optimization and Characterization of Propolis-Loaded Solid Lipid Nanoparticles Using Box-Behnken Design
por: Taherzadeh, Sahar, et al.
Publicado: (2021)

Solid Lipid Nanoparticles Embedded Hydrogels as a Promising Carrier for Retarding Irritation of Leflunomide
por: Alhelal, Hawra Mohammed, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jg2hqdk3daptcquqn06663i2k6