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The Design and Synthesis of a New Class of RTK/HDAC Dual-Targeted Inhibitors

Over the years, the development of targeted medicines has made significant achievements. As a typical example, receptor tyrosine kinases (RTK) inhibitors have become important chemotherapy drugs for a variety of cancers. However, the effectiveness of these agents is always hindered by poor response...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Su, Mingbo, Chen, Yi, Li, Jia, Lu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269723/
https://www.ncbi.nlm.nih.gov/pubmed/23736786
http://dx.doi.org/10.3390/molecules18066491