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Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

New hetaryl- and alkylidenerhodanine derivatives 3a–d, 3e, and 4a–d were prepared from heterocyclic aldehydes 1a–d or acetaldehyde 1e. The treatment of several rhodanine derivatives 3a–d and 3e with piperidine or morpholine in THF under reflux, afforded (Z)-5-(hetarylmethylidene)-2-(piperidin-1-yl)t...

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Detalles Bibliográficos
Autores principales: Insuasty, Alberto, Ramírez, Juan, Raimondi, Marcela, Echeverry, Carlos, Quiroga, Jairo, Abonia, Rodrigo, Nogueras, Manuel, Cobo, Justo, Rodríguez, María Victoria, Zacchino, Susana A., Insuasty, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269731/
https://www.ncbi.nlm.nih.gov/pubmed/23669632
http://dx.doi.org/10.3390/molecules18055482