Intravenous and Subcutaneous Toxicity and Absorption Kinetics in Mice and Dogs of the Antileishmanial Triterpene Saponin PX-6518

The intravenous (IV) and subcutaneous (SC) toxicity and absorption kinetics of the antileishmanial triterpene saponin PX-6518 and its active constituents maesabalide-III and -IV were studied in mice and dogs. A high-dose wash-out study of PX-6518 at 20 mg/kg SC for 5 days and a single low-dose wash-...

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Detalles Bibliográficos
Autor principal: Maes, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269738/
https://www.ncbi.nlm.nih.gov/pubmed/23609628
http://dx.doi.org/10.3390/molecules18044803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269738/
https://www.ncbi.nlm.nih.gov/pubmed/23609628
http://dx.doi.org/10.3390/molecules18044803

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