A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin

A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5-(1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl)carbonyl]-1H-pyrrole-3-carboxylates were prepared in excellent yields (82-98%) by one-pot reactions between β-dicarbonyl compounds 12a–e and 1,2-diaza-1,3-diene (DD) 13. Deriva...

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Detalles Bibliográficos
Autores principales: Carbone, Anna, Spanò, Virginia, Parrino, Barbara, Ciancimino, Cristina, Attanasi, Orazio A., Favi, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269752/
https://www.ncbi.nlm.nih.gov/pubmed/23442928
http://dx.doi.org/10.3390/molecules18032518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269752/
https://www.ncbi.nlm.nih.gov/pubmed/23442928
http://dx.doi.org/10.3390/molecules18032518

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