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A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin
A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5-(1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl)carbonyl]-1H-pyrrole-3-carboxylates were prepared in excellent yields (82-98%) by one-pot reactions between β-dicarbonyl compounds 12a–e and 1,2-diaza-1,3-diene (DD) 13. Deriva...
Autores principales: | Carbone, Anna, Spanò, Virginia, Parrino, Barbara, Ciancimino, Cristina, Attanasi, Orazio A., Favi, Gianfranco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269752/ https://www.ncbi.nlm.nih.gov/pubmed/23442928 http://dx.doi.org/10.3390/molecules18032518 |
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