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Chitosan Rate of Uptake in HEK293 Cells is Influenced by Soluble versus Microparticle State and Enhanced by Serum-Induced Cell Metabolism and Lactate-Based Media Acidification

Chitosan is a biocompatible polysaccharide composed of glucosamine and N-acetylglucosamine. The polymer has a unique behavior of fluctuating between soluble chains at pH 6 and insoluble microparticles at pH 7. The purpose of this study was to test the hypothesis that chitosan structure, solubility s...

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Detalles Bibliográficos
Autores principales: Hoemann, Caroline D., Guzmán-Morales, Jessica, Tran-Khanh, Nicolas, Lavallée, Geneviève, Jolicoeur, Mario, Lavertu, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269786/
https://www.ncbi.nlm.nih.gov/pubmed/23322067
http://dx.doi.org/10.3390/molecules18011015