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Chitosan Rate of Uptake in HEK293 Cells is Influenced by Soluble versus Microparticle State and Enhanced by Serum-Induced Cell Metabolism and Lactate-Based Media Acidification
Chitosan is a biocompatible polysaccharide composed of glucosamine and N-acetylglucosamine. The polymer has a unique behavior of fluctuating between soluble chains at pH 6 and insoluble microparticles at pH 7. The purpose of this study was to test the hypothesis that chitosan structure, solubility s...
Autores principales: | Hoemann, Caroline D., Guzmán-Morales, Jessica, Tran-Khanh, Nicolas, Lavallée, Geneviève, Jolicoeur, Mario, Lavertu, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269786/ https://www.ncbi.nlm.nih.gov/pubmed/23322067 http://dx.doi.org/10.3390/molecules18011015 |
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