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4862F, a New Inhibitor of HIV-1 Protease, from the Culture of Streptomyces I03A-04862

We have isolated an extraordinary pentapeptide, called 4862F, from the culture broth of Streptomyces albosporus I03A-04862 by Diaion HP-20 macroporous adsorbent resin column, ODS-A and Sephadex LH-20 chromatography, followed by preparative HPLC. This peptide shows inhibitory activity against HIV-1 p...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Gan, Maoluo, Dong, Biao, Zhang, Tian, Li, Yongzhen, Zhang, Yuqin, Fan, Xiuyong, Wu, Yexiang, Bai, Shuoke, Chen, Minghua, Yu, Liyan, Tao, Peizhen, Jiang, Wei, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269790/
https://www.ncbi.nlm.nih.gov/pubmed/23271463
http://dx.doi.org/10.3390/molecules18010236