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Arylsulfonylamino-Benzanilides as Inhibitors of the Apical Sodium-Dependent Bile Salt Transporter (SLC10A2)

The apical sodium-dependent bile salt transporter (ASBT) plays a pivotal role in maintaining bile acid homeostasis. Inhibition of ASBT would reduce bile acid pool size and lower cholesterol levels. In this report, a series of novel arylsulfonylaminobenzanilides were designed and synthesized as poten...

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Detalles Bibliográficos
Autores principales: Liu, Hong-Tao, He, Hong-Wei, Bai, Xiao-Guang, Wang, Ju-Xian, Xu, Chang-Liang, Cai, Shi-Ying, Shao, Rong-Guang, Wang, Yu-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269792/
https://www.ncbi.nlm.nih.gov/pubmed/23752471
http://dx.doi.org/10.3390/molecules18066883