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Synthesis and Dual Histamine H(1) and H(2) Receptor Antagonist Activity of Cyanoguanidine Derivatives

Premedication with a combination of histamine H(1) receptor (H(1)R) and H(2) receptor (H(2)R) antagonists has been suggested as a prophylactic principle, for instance, in anaesthesia and surgery. Aiming at pharmacological hybrids combining H(1)R and H(2)R antagonistic activity, a series of cyanoguan...

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Detalles Bibliográficos
Autores principales: Sadek, Bassem, Alisch, Rudi, Buschauer, Armin, Elz, Sigurd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269795/
https://www.ncbi.nlm.nih.gov/pubmed/24248146
http://dx.doi.org/10.3390/molecules181114186