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Synthesis and Dual Histamine H(1) and H(2) Receptor Antagonist Activity of Cyanoguanidine Derivatives
Premedication with a combination of histamine H(1) receptor (H(1)R) and H(2) receptor (H(2)R) antagonists has been suggested as a prophylactic principle, for instance, in anaesthesia and surgery. Aiming at pharmacological hybrids combining H(1)R and H(2)R antagonistic activity, a series of cyanoguan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269795/ https://www.ncbi.nlm.nih.gov/pubmed/24248146 http://dx.doi.org/10.3390/molecules181114186 |