Synthesis and Trypanocidal Activity of Novel 2,4,5-Triaryl-N-Hydroxylimidazole Derivatives

Herein, we report the design, synthesis and trypanocidal activity of some novel trisubstituted imidazole derivatives. These heterocyclic derivatives were structurally planned by exploring the concept of molecular hybridisation between two arylhydrazones derived from megazol, which has potent trypano...

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Detalles Bibliográficos
Autores principales: da Silva, Ramon Borges, Loback, Vanessa Brandão, Salomão, Kelly, de Castro, Solange Lisboa, Wardell, James L., Wardell, Solange M. S. V., Costa, Thadeu Estevam Moreira Maramaldo, Penido, Carmen, Henriques, Maria das Graças Muller de Oliveira, Carvalho, Samir Aquino, da Silva, Edson Ferreira, Fraga, Carlos Alberto Manssour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269799/
https://www.ncbi.nlm.nih.gov/pubmed/23503118
http://dx.doi.org/10.3390/molecules18033445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269799/
https://www.ncbi.nlm.nih.gov/pubmed/23503118
http://dx.doi.org/10.3390/molecules18033445

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