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Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update

Cyclooxygenase-2 (COX-2) is a key player in inflammation. Its overexpression is directly associated with various inflammatory diseases and, additionally, with several processes of carcinogenesis. The development of new selective COX-2 inhibitors (COXIBs) for use in cancer treatment is in the focus o...

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Detalles Bibliográficos
Autores principales: Laube, Markus, Kniess, Torsten, Pietzsch, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269837/
https://www.ncbi.nlm.nih.gov/pubmed/23760031
http://dx.doi.org/10.3390/molecules18066311