Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles

Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior. The solution phase approach was tedious and involved cyclization of a ridged heterocyclic precursor, while solid pha...

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Detalles Bibliográficos
Autores principales: Kim, Seong Jong, McAlpine, Shelli R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269862/
https://www.ncbi.nlm.nih.gov/pubmed/23325099
http://dx.doi.org/10.3390/molecules18011111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269862/
https://www.ncbi.nlm.nih.gov/pubmed/23325099
http://dx.doi.org/10.3390/molecules18011111

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