Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues. In addition, biotin may facilitate delivery of de...

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Detalles Bibliográficos
Autores principales: Hemmer, Ruth, Hall, Andrew, Spaulding, Robert, Rossow, Brett, Hester, Michael, Caroway, Megan, Haskamp, Anthony, Wall, Steven, Bullen, Heather A., Morris, Celeste, Haik, Kristi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269868/
https://www.ncbi.nlm.nih.gov/pubmed/24048286
http://dx.doi.org/10.3390/molecules180911537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269868/
https://www.ncbi.nlm.nih.gov/pubmed/24048286
http://dx.doi.org/10.3390/molecules180911537

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