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Synthesis and Structure-Activity Relationships of Novel Ecdysteroid Dioxolanes as MDR Modulators in Cancer

Ecdysteroids, molting hormones of insects, can exert several mild, non-hormonal bioactivities in mammals, including humans. In a previous study, we have found a significant effect of certain derivatives on the ABCB1 transporter mediated multi-drug resistance of a transfected murine leukemia cell lin...

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Detalles Bibliográficos
Autores principales: Martins, Ana, Csábi, József, Balázs, Attila, Kitka, Diána, Amaral, Leonard, Molnár, József, Simon, András, Tóth, Gábor, Hunyadi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269874/
https://www.ncbi.nlm.nih.gov/pubmed/24335576
http://dx.doi.org/10.3390/molecules181215255