Original TDAE Strategy Using Propargylic Chloride: Rapid Access to 1,4-Diarylbut-3-ynol Derivatives

We report herein the first synthesis of propargylic alcohols using an organic reducing agent. Diarylbutynol derivatives are formed in moderate to good yields under mild conditions from the reaction of 1-(3-chloroprop-1-ynyl)-4-nitrobenzene with various aromatic aldehydes using tetrakis(dimethylamino...

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Detalles Bibliográficos
Autores principales: Roche, Manon, Terme, Thierry, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269883/
https://www.ncbi.nlm.nih.gov/pubmed/23353124
http://dx.doi.org/10.3390/molecules18021540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269883/
https://www.ncbi.nlm.nih.gov/pubmed/23353124
http://dx.doi.org/10.3390/molecules18021540

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