Novel Substituted Heteroaromatic Piperazine and Piperidine Derivatives as Inhibitors of Human Enterovirus 71 and Coxsackievirus A16

A series of substituted heteroaromatic piperazine and piperidine derivatives were found through virtual screening based on the structure of human enterovirus 71 capsid protein VP1. The preliminary biological evaluation revealed that compounds 8e and 9e have potent activity against EV71 and Coxsackie...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xian, Wang, Hongliang, Li, Yuhuan, Cao, Ruiyuan, Zhong, Wu, Zheng, Zhibing, Wang, Gang, Xiao, Junhai, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269887/
https://www.ncbi.nlm.nih.gov/pubmed/23629759
http://dx.doi.org/10.3390/molecules18055059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269887/
https://www.ncbi.nlm.nih.gov/pubmed/23629759
http://dx.doi.org/10.3390/molecules18055059

Ejemplares similares