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Synthesis and Characterization of Celecoxib Derivatives as Possible Anti-Inflammatory, Analgesic, Antioxidant, Anticancer and Anti-HCV Agents †

A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamides 2a–e were synthesized by the addition of ethyl α-bromoacetate and anhydrous sodium acetate in dry ethanol to N-(substituted aryl/alkylcarbamoth...

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Detalles Bibliográficos
Autores principales: Küçükgüzel, Ş. Güniz, Coşkun, İnci, Aydın, Sevil, Aktay, Göknur, Gürsoy, Şule, Çevik, Özge, Özakpınar, Özlem Bingöl, Özsavcı, Derya, Şener, Azize, Kaushik-Basu, Neerja, Basu, Amartya, Talele, Tanaji T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269910/
https://www.ncbi.nlm.nih.gov/pubmed/23519201
http://dx.doi.org/10.3390/molecules18033595