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Synthesis and Biological Evaluation of Apigenin Derivatives as Antibacterial and Antiproliferative Agents

Two series of apigenin [5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one] derivatives, 3a–3j and 4a–4j, were synthesized. The apigenin and alkyl amines moieties of these compounds were separated by C(2) or C(3) spacers, respectively. The chemical structures of the apigenin derivatives were confirm...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Zhang, Hongchi, Yuan, Maosen, Zhou, Jiao, Tu, Qin, Liu, Jian-Jun, Wang, Jinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269912/
https://www.ncbi.nlm.nih.gov/pubmed/24048283
http://dx.doi.org/10.3390/molecules180911496