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In Vitro Evaluation of Novel Inhibitors against the NS2B-NS3 Protease of Dengue Fever Virus Type 4

The discovery of potent therapeutic compounds against dengue virus is urgently needed. The NS2B-NS3 protease (NS2B-NS3(pro)) of dengue fever virus carries out all enzymatic activities needed for polyprotein processing and is considered to be amenable to antiviral inhibition by analogy. Virtual scree...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Thanh Hanh, Lee, Sun, Wang, Hsi-Kai, Chen, Hsin-Yen, Wu, Ying-Ta, Lin, Simon C., Kim, Do-Won, Kim, Doman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269914/
https://www.ncbi.nlm.nih.gov/pubmed/24352016
http://dx.doi.org/10.3390/molecules181215600