Cargando…
Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones
Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee.
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269931/ https://www.ncbi.nlm.nih.gov/pubmed/24287989 http://dx.doi.org/10.3390/molecules181214529 |
| _version_ | 1783376581978226688 |
|---|---|
| author | Nakashima, Kosuke Murahashi, Miho Yuasa, Hiroki Ina, Mariko Tada, Norihiro Itoh, Akichika Hirashima, Shin-ichi Koseki, Yuji Miura, Tsuyoshi |
| author_facet | Nakashima, Kosuke Murahashi, Miho Yuasa, Hiroki Ina, Mariko Tada, Norihiro Itoh, Akichika Hirashima, Shin-ichi Koseki, Yuji Miura, Tsuyoshi |
| author_sort | Nakashima, Kosuke |
| collection | PubMed |
| description | Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee. |
| format | Online Article Text |
| id | pubmed-6269931 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2013 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-62699312018-12-20 Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones Nakashima, Kosuke Murahashi, Miho Yuasa, Hiroki Ina, Mariko Tada, Norihiro Itoh, Akichika Hirashima, Shin-ichi Koseki, Yuji Miura, Tsuyoshi Molecules Article Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee. MDPI 2013-11-25 /pmc/articles/PMC6269931/ /pubmed/24287989 http://dx.doi.org/10.3390/molecules181214529 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| spellingShingle | Article Nakashima, Kosuke Murahashi, Miho Yuasa, Hiroki Ina, Mariko Tada, Norihiro Itoh, Akichika Hirashima, Shin-ichi Koseki, Yuji Miura, Tsuyoshi Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title | Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title_full | Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title_fullStr | Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title_full_unstemmed | Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title_short | Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones |
| title_sort | perfluoroalkanesulfonamide organocatalysts for asymmetric conjugate additions of branched aldehydes to vinyl sulfones |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269931/ https://www.ncbi.nlm.nih.gov/pubmed/24287989 http://dx.doi.org/10.3390/molecules181214529 |
| work_keys_str_mv | AT nakashimakosuke perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT murahashimiho perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT yuasahiroki perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT inamariko perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT tadanorihiro perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT itohakichika perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT hirashimashinichi perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT kosekiyuji perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones AT miuratsuyoshi perfluoroalkanesulfonamideorganocatalystsforasymmetricconjugateadditionsofbranchedaldehydestovinylsulfones |