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Efficient Synthesis of a (Z)-3-Methyleneisoindolin-1-one Library Using Cu(OAc)(2)•H(2)O/DBU under Microwave Irradiation
Microwave-promoted efficient synthesis of a (Z)-3-methyleneisoindolin-1-one library from 2-bromobenzamides and terminal alkynes using Cu(OAc)(2)•H(2)O/DBU is described. Various benzamide substituents, ring substitutions, including heteroaryl, aryl acetylenes and aliphatic alkynes, could be applied t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269936/ https://www.ncbi.nlm.nih.gov/pubmed/23292328 http://dx.doi.org/10.3390/molecules18010654 |