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Efficient Synthesis of a (Z)-3-Methyleneisoindolin-1-one Library Using Cu(OAc)(2)•H(2)O/DBU under Microwave Irradiation

Microwave-promoted efficient synthesis of a (Z)-3-methyleneisoindolin-1-one library from 2-bromobenzamides and terminal alkynes using Cu(OAc)(2)•H(2)O/DBU is described. Various benzamide substituents, ring substitutions, including heteroaryl, aryl acetylenes and aliphatic alkynes, could be applied t...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Zhang, Yongliang, Wang, Xin, Shen, Jingkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269936/
https://www.ncbi.nlm.nih.gov/pubmed/23292328
http://dx.doi.org/10.3390/molecules18010654