2-(Substituted phenyl)-3,4-dihydroisoquinolin-2-iums as Novel Antifungal Lead Compounds: Biological Evaluation and Structure-Activity Relationships

The title compounds are a class of structurally simple analogues of quaternary benzo[c]phenanthridine alkaloids (QBAs). In order to develop novel QBA-like antifungal drugs, in this study, 24 of the title compounds with various substituents on the N-phenyl ring were evaluated for bioactivity against...

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Detalles Bibliográficos
Autores principales: Hou, Zhe, Yang, Rui, Zhang, Cen, Zhu, Li-Fei, Miao, Fang, Yang, Xin-Juan, Zhou, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269970/
https://www.ncbi.nlm.nih.gov/pubmed/23994968
http://dx.doi.org/10.3390/molecules180910413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269970/
https://www.ncbi.nlm.nih.gov/pubmed/23994968
http://dx.doi.org/10.3390/molecules180910413

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