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2-(Substituted phenyl)-3,4-dihydroisoquinolin-2-iums as Novel Antifungal Lead Compounds: Biological Evaluation and Structure-Activity Relationships
The title compounds are a class of structurally simple analogues of quaternary benzo[c]phenanthridine alkaloids (QBAs). In order to develop novel QBA-like antifungal drugs, in this study, 24 of the title compounds with various substituents on the N-phenyl ring were evaluated for bioactivity against...
Autores principales: | Hou, Zhe, Yang, Rui, Zhang, Cen, Zhu, Li-Fei, Miao, Fang, Yang, Xin-Juan, Zhou, Le |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269970/ https://www.ncbi.nlm.nih.gov/pubmed/23994968 http://dx.doi.org/10.3390/molecules180910413 |
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