Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-ribityl or 4-Hydroxybutyl Chains in Place of the Ribose

The antiviral activity of certain acyclic nucleosides drew our attention to the fact that the replacement of the furanose ring by an alkyl group bearing hydroxyl(s) could be a useful structural modification to modulate the biological properties of those nucleosides. Herein, we report on the synthesi...

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Detalles Bibliográficos
Autores principales: D’Errico, Stefano, Oliviero, Giorgia, Borbone, Nicola, Amato, Jussara, Piccialli, Vincenzo, Varra, Michela, Mayol, Luciano, Piccialli, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269997/
https://www.ncbi.nlm.nih.gov/pubmed/23924994
http://dx.doi.org/10.3390/molecules18089420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269997/
https://www.ncbi.nlm.nih.gov/pubmed/23924994
http://dx.doi.org/10.3390/molecules18089420

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