5-Episinuleptolide Acetate, a Norcembranoidal Diterpene from the Formosan Soft Coral Sinularia sp., Induces Leukemia Cell Apoptosis through Hsp90 Inhibition

5-Episinuleptolide acetate (5EPA), a cytotoxic norcembranoidal diterpene recently identified from the Formosan soft coral Sinularia sp., exhibited potent activity against the K562, Molt 4 and HL 60 cancer cell lines. The antiproliferative assay, as well as the annexin V-FITC/propidium iodide (PI) ap...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Kao-Jean, Chen, Yu-Cheng, El-Shazly, Mohamed, Du, Ying-Chi, Su, Jui-Hsin, Tsao, Chia-Wei, Yen, Wei-Hsuan, Chang, Wen-Been, Su, Yin-Di, Yeh, Yao-Tsung, Lu, Mei-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270000/
https://www.ncbi.nlm.nih.gov/pubmed/23459302
http://dx.doi.org/10.3390/molecules18032924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270000/
https://www.ncbi.nlm.nih.gov/pubmed/23459302
http://dx.doi.org/10.3390/molecules18032924

Ejemplares similares