Synthesis and Antiviral Activity of N-Phenylbenzamide Derivatives, a Novel Class of Enterovirus 71 Inhibitors

A series of novel N-phenylbenzamide derivatives were synthesized and their anti-EV 71 activities were assayed in vitro. Among the compounds tested, 3-amino-N-(4-bromophenyl)-4-methoxybenzamide (1e) was active against the EV 71 strains tested at low micromolar concentrations, with IC(50) values rangi...

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Detalles Bibliográficos
Autores principales: Ji, Xing-Yue, Wang, Hui-Qiang, Hao, Lan-Hu, He, Wei-Ying, Gao, Rong-Mei, Li, Yan-Ping, Li, Yu-Huan, Jiang, Jian-Dong, Li, Zhuo-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270001/
https://www.ncbi.nlm.nih.gov/pubmed/23519203
http://dx.doi.org/10.3390/molecules18033630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270001/
https://www.ncbi.nlm.nih.gov/pubmed/23519203
http://dx.doi.org/10.3390/molecules18033630

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