Synthesis and Biological Evaluation of Thieno[3,2-d]- pyrimidinones, Thieno[3,2-d]pyrimidines and Quinazolinones: Conformationally Restricted 17β-Hydroxysteroid Dehydrogenase Type 2 (17β-HSD2) Inhibitors

In this study, a series of conformationally restricted thieno[3,2-d]pyrimidinones, thieno[3,2-d]pyrimidines and quinazolinones was designed and synthesized with the goal of improving the biological activity as 17β-hydroxysteroid dehydrogenase type 2 inhibitors of the corresponding amidothiophene der...

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Detalles Bibliográficos
Autores principales: Perspicace, Enrico, Marchais-Oberwinkler, Sandrine, Hartmann, Rolf W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270028/
https://www.ncbi.nlm.nih.gov/pubmed/23591928
http://dx.doi.org/10.3390/molecules18044487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270028/
https://www.ncbi.nlm.nih.gov/pubmed/23591928
http://dx.doi.org/10.3390/molecules18044487

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