Highly Enantioselective Addition of Phenylethynylzinc to Aldehydes Catalyzed by Chiral Cyclopropane-Based Amino Alcohols

The enantioselective addition of phenylethynylzinc to aldehydes catalyzed by a series of cyclopropane-based amino alcohol ligands 7 was investigated. The reactions afforded chiral propargylic alcohols in high yields (up to 96%) and with excellent enantioselectivities (up to 98% ee) under mild condit...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Bing, Li, Zhiyuan, Liu, Feipeng, Wu, Yanhua, Shen, Junjian, Bian, Qinghua, Hou, Shicong, Wang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270052/
https://www.ncbi.nlm.nih.gov/pubmed/24335619
http://dx.doi.org/10.3390/molecules181215422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270052/
https://www.ncbi.nlm.nih.gov/pubmed/24335619
http://dx.doi.org/10.3390/molecules181215422

Ejemplares similares