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Novel Antimicrobial Peptide Dendrimers with Amphiphilic Surface and Their Interactions with Phospholipids — Insights from Mass Spectrometry

A series of new peptide dendrimers with amphiphilic surface, designed around a dendronized ornithine (Orn) core were synthesized and characterized by ESI-MS, (1)H-, (13)C- NMR, and CD spectrometry. An improved antimicrobial potency against S. aureus and E. coli was detected as a result of an increas...

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Detalles Bibliográficos
Autores principales: Polcyn, Piotr, Zielinska, Paulina, Zimnicka, Magdalena, Troć, Anna, Kalicki, Przemysław, Solecka, Jolanta, Laskowska, Anna, Urbanczyk-Lipkowska, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270063/
https://www.ncbi.nlm.nih.gov/pubmed/23778121
http://dx.doi.org/10.3390/molecules18067120