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Examination of the Potential for Adaptive Chirality of the Nitrogen Chiral Center in Aza-Aspartame

The potential for dynamic chirality of an azapeptide nitrogen was examined by substitution of nitrogen for the α-carbon of the aspartate residue in the sweetener S,S-aspartame. Considering that S,S- and R,S-aspartame possess sweet and bitter tastes, respectively, a bitter-sweet taste of aza-aspartam...

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Detalles Bibliográficos
Autores principales: Bouayad-Gervais, Samir H., Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270076/
https://www.ncbi.nlm.nih.gov/pubmed/24288001
http://dx.doi.org/10.3390/molecules181214739