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Examination of the Potential for Adaptive Chirality of the Nitrogen Chiral Center in Aza-Aspartame
The potential for dynamic chirality of an azapeptide nitrogen was examined by substitution of nitrogen for the α-carbon of the aspartate residue in the sweetener S,S-aspartame. Considering that S,S- and R,S-aspartame possess sweet and bitter tastes, respectively, a bitter-sweet taste of aza-aspartam...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270076/ https://www.ncbi.nlm.nih.gov/pubmed/24288001 http://dx.doi.org/10.3390/molecules181214739 |