Synthesis of DNA/RNA and Their Analogs via Phosphoramidite and H-Phosphonate Chemistries

The chemical synthesis of DNA and RNA is universally carried out using nucleoside phosphoramidites or H-phosphonates as synthons. This review focuses on the phosphorus chemistry behind these synthons and how it has been developed to generate procedures whereby yields per condensation approach 100% w...

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Detalles Bibliográficos
Autores principales: Roy, Subhadeep, Caruthers, Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270087/
https://www.ncbi.nlm.nih.gov/pubmed/24252996
http://dx.doi.org/10.3390/molecules181114268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270087/
https://www.ncbi.nlm.nih.gov/pubmed/24252996
http://dx.doi.org/10.3390/molecules181114268

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