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Pd(0)-Catalyzed Methyl Transfer on Nucleosides and Oligonucleotides, Envisaged as a PET Tracer

The methyl transfer reaction from activated monomethyltin, via a modified Stille coupling reaction, was studied under “ligandless” conditions on fully deprotected 5'-modified nucleosides and one dinucleotide. The reaction was optimized to proceed in a few minutes and quantitative yield, even un...

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Detalles Bibliográficos
Autores principales: James, Damien, Escudier, Jean-Marc, Szlosek-Pinaud, Magali, Fouquet, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270090/
https://www.ncbi.nlm.nih.gov/pubmed/24196412
http://dx.doi.org/10.3390/molecules181113654