Dibenzo[1,2,5]thiadiazepines Are Non-Competitive GABA(A) Receptor Antagonists

A new process for obtaining dibenzo[c,f][1,2,5]thiadiazepines (DBTDs) and their effects on GABA(A) receptors of guinea pig myenteric neurons are described. Synthesis of DBTD derivatives began with two commercial aromatic compounds. An azide group was obtained after two sequential reactions, and the...

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Detalles Bibliográficos
Autores principales: Ramírez-Martínez, Juan F., González-Chávez, Rodolfo, Guerrero-Alba, Raquel, Reyes-Gutiérrez, Paul E., Martínez, Roberto, Miranda-Morales, Marcela, Espinosa-Luna, Rosa, González-Chávez, Marco M., Barajas-López, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270094/
https://www.ncbi.nlm.nih.gov/pubmed/23344200
http://dx.doi.org/10.3390/molecules18010894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270094/
https://www.ncbi.nlm.nih.gov/pubmed/23344200
http://dx.doi.org/10.3390/molecules18010894

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