Facile Creation of 3-Substituted-3-Hydroxy-2-Oxindoles by Arginine-Catalyzed Aldol Reactions of α,β-Unsaturated Ketones with Isatins

An efficient approach for the synthesis of 3-substituted-3-hydroxy-2-oxindoles has been achieved via an aldol reaction of α,β-unsaturated ketones and isatins using arginine as an organocatalyst. A range of 3-substituted-3-hydroxy-2-oxindoles were obtained in moderate to high (up to 99%) yields. Thes...

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Detalles Bibliográficos
Autores principales: Yan, Tingting, Wang, Xiaoyan, Sun, Hongbao, Liu, Jie, Xie, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270100/
https://www.ncbi.nlm.nih.gov/pubmed/24287987
http://dx.doi.org/10.3390/molecules181214505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270100/
https://www.ncbi.nlm.nih.gov/pubmed/24287987
http://dx.doi.org/10.3390/molecules181214505

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