Application of Reductive (13)C-Methylation of Lysines to Enhance the Sensitivity of Conventional NMR Methods

NMR is commonly used to investigate macromolecular interactions. However, sensitivity problems hamper its use for studying such interactions at low physiologically relevant concentrations. At high concentrations, proteins or peptides tend to aggregate. In order to overcome this problem, we make use...

Descripción completa

Detalles Bibliográficos
Autores principales: Chavan, Tanmay S., Abraham, Sherwin, Gaponenko, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270119/
https://www.ncbi.nlm.nih.gov/pubmed/23778120
http://dx.doi.org/10.3390/molecules18067103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270119/
https://www.ncbi.nlm.nih.gov/pubmed/23778120
http://dx.doi.org/10.3390/molecules18067103

Ejemplares similares