3D-QSAR and Cell Wall Permeability of Antitubercular Nitroimidazoles against Mycobacterium tuberculosis

Inhibitory activities of monocyclic nitroimidazoles against Mycobacterium tuberculosis (Mtb) deazaflavin-dependent nitroreductase (DDN) were modeled by using docking, pharmacophore alignment and comparative molecular similarity indices analysis (CoMSIA) methods. A statistically significant model obt...

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Detalles Bibliográficos
Autores principales: Lee, Sang-Ho, Choi, Minsung, Kim, Pilho, Myung, Pyung Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270125/
https://www.ncbi.nlm.nih.gov/pubmed/24217328
http://dx.doi.org/10.3390/molecules181113870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270125/
https://www.ncbi.nlm.nih.gov/pubmed/24217328
http://dx.doi.org/10.3390/molecules181113870

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