Synthesis, DNA Binding and Topoisomerase I Inhibition Activity of Thiazacridine and Imidazacridine Derivatives

Thiazacridine and imidazacridine derivatives have shown promising results as tumors suppressors in some cancer cell lines. For a better understanding of the mechanism of action of these compounds, binding studies of 5-acridin-9-ylmethylidene-3-amino-2-thioxo-thiazolidin-4-one, 5-acridin-9-ylmethylid...

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Detalles Bibliográficos
Autores principales: Lafayette, Elizabeth Almeida, de Almeida, Sinara Mônica Vitalino, da Rocha Pitta, Marina Galdino, Beltrão, Eduardo Isidoro Carneiro, da Silva, Teresinha Gonçalves, de Moura, Ricardo Olímpio, da Rocha Pitta, Ivan, de Carvalho, Luiz Bezerra, do Carmo Alves de Lima, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270168/
https://www.ncbi.nlm.nih.gov/pubmed/24322489
http://dx.doi.org/10.3390/molecules181215035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270168/
https://www.ncbi.nlm.nih.gov/pubmed/24322489
http://dx.doi.org/10.3390/molecules181215035

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