Design, Synthesis and Biological Evaluation of N-Sulfonyl Homoserine Lactone Derivatives as Inhibitors of Quorum Sensing in Chromobacterium violaceum

A novel series of N-sulfonyl homoserine lactone derivatives 5a–l has been designed, synthesized and evaluated for quorum sensing inhibitory activities towards violacein production. Of the compounds synthesized, compound 5h was found to possess an excellent level of enantiopurity (99.2% e.e.). The re...

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Detalles Bibliográficos
Autores principales: Zhao, Mingming, Yu, Yingying, Hua, Yuhui, Feng, Fan, Tong, Yigang, Yang, Xiaohong, Xiao, Junhai, Song, Hongrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270181/
https://www.ncbi.nlm.nih.gov/pubmed/23486105
http://dx.doi.org/10.3390/molecules18033266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270181/
https://www.ncbi.nlm.nih.gov/pubmed/23486105
http://dx.doi.org/10.3390/molecules18033266

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